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Stabholz A, Shapira L, Mahler D, Gellman Y, Ramon T, Dolev E,
Schwartz M, Berger L, Proskin HM, Finkelman RD, Flashner M, Kolatch B,
Soskolne A.
Department of Community Dentistry, Hebrew University, Hadassah Faculty
of Dental Medicine, Jerusalem, Israel.
Multicenter clinical trials have established that the adjunctive use
of the subgingival controlled release of chlorhexidine, in the form of
the PerioChip, significantly reduces pocket probing depth, improves
probing attachment levels, and reduces bleeding on probing compared to
scaling and root planing alone, for periods up to 9 months. The
purpose of the present study was to report on the adjunctive use of
the PerioChip for the long-term management of adult periodontitis for
2 years. A total of 836 patients with adult periodontitis from private
dental offices were recruited into the trial. This interim report is
on the first 72 patients to have completed the 2-year study.
Treatments included initial definitive therapy followed by PerioChip
placement in pocket sites with a pocket probing depth of > or = 5
mm after 1 month. Subsequently, the patients received routine
periodontal maintenance therapy together with the placement of a
PerioChip in pockets with pocket probing depths > or = 5 mm every 3
months. Results indicated that there was a continuous decrease in
pocket probing depth over the 2 years (1.26 +/- 0.77 mm). This
decrease in pocket probing depth was marked over the first 9 to 12
months, and then appeared to be less marked over the next 12 months.
At 2 years, 60% of the patients had at least 2 pockets showing a
reduction of 2 mm or more, and only 10% of the patients showed no
change or increased pocket probing depth. The results indicate that
adjunctive PerioChip use is a clinically effective treatment option
for dental professionals and their patients for the long-term
management of adult periodontitis.
Publication Types:
PMID: 11199684 [PubMed - indexed for MEDLINE]
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